Background It has been demonstrated that nintedanib can inhibit the proliferation of gastric cancer cells, but the specific mechanism of action is unclear.Objective Investigating the changes of key factors involved in gene transcription and post-transcriptional regulation during the process of treating gastric cancer with nintedanib.Methods In this
Several studies suggest the relation of DNA methylation to diseases in humans and important phenotypes in plants drawing attention to this epigenetic mark as an important source of variability.In the last decades, several methodologies were developed to assess the methylation state of a genome.However, there is still a lack of affordable and precis
Background & Aims: Breast regression protein 39 (BRP39) (Chi3L1) and its human homolog YKL-40, is an established biomarker of liver fibrosis in nonalcoholic steatohepatitis (NASH) patients, but its role in NASH pathogenesis remains unclear.We recently identified Chi3L1 as one of the top up-regulated genes AC Adapter in mice with inducible gain-
The Greater Bird-of-Paradise (Paradisaea apoda) is a bird that performs a courtship display (lekking) to attract females during the mating season.The objective of this study was to examine the display behavior of adult and sub-adult males on lek Dresser trees as a learning process by a sub-adult and identify the lek trees.The research was conducted
Covalent organic frameworks comprise a unique class of functional materials that has recently emerged as a versatile tool for energy-related, photocatalytic, environmental, and electrochromic device applications.A plethora of structures can be designed and implemented through a careful selection of ligands and functional units.On the other hand, po